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The Dog-First Cancer Revolution
How Calviri is rewriting oncology with a bold, pet-first strategy
While most biotechs chase human trials directly, Calviri took a radical detour: proving cancer vaccines on dogs first. It's a masterclass in de-risking the most expensive science on Earth.
"They're not building a pet company—they're building a human cancer company with the smartest clinical trial platform on the market."
The Strategy: De-risk by Design
Calviri's thesis is brutally elegant. Canine cancer patients are genetically closer to humans than mice, have faster disease progression, and live in homes with owners who pay out-of-pocket. By validating vaccines in dogs first, they gather real-world efficacy data at a fraction of the human trial cost—while generating revenue from the very start. It's a dual-market flywheel that most pharma giants would kill for.
The Numbers Don't Lie
With just $9.3M in funding, Calviri has achieved what typically requires $50M+. Their $2.2M revenue proves the canine market is viable, not just theoretical. The 28-person team is leaner than a typical Series A biotech, yet they've built a proprietary vaccine platform and a manufacturing pipeline. Every dollar is working overtime here.
The tech stack reveals their priorities: React for speed, Bootstrap for rapid iteration, and Zendesk for customer service—because in the pet market, experience is everything. They're not building a lab-first company; they're building a customer-first biotech.
- First-mover in canine cancer vaccines as a clinical validation platform
- Revenue-positive while in R&D (extremely rare in biotech)
- Dual-market strategy de-risks human trials
- Lean team executes at startup speed with pharma-grade science
This is how you end cancer
Not by following the herd, but by building a smarter, faster, cheaper path to human trials. Calviri's dog-first approach might be the most underappreciated innovation in oncology today.
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Calviri | Cancer Diagnostics and Vaccines
Calviri | Let's End Cancer. First Dogs, Then People.
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Calviri | Let's End Cancer. First Dogs, Then People.
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