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Pharvaris: The Oral HAE Disruptor
A late-stage biopharma betting big on oral bradykinin B2 receptor antagonists
Pharvaris isn't just another biopharma site; it's a single-track missile aimed at the $2B+ hereditary angioedema (HAE) market. While competitors rely on injections, this late-stage company is betting the farm on a simple promise: stop the attack, orally.
"They aren't fighting the needle—they're eliminating it. In a market dominated by injectables, an oral B2 antagonist is the ultimate differentiator."
The Product Focus
Pharvaris is laser-focused on hereditary angioedema (HAE), a rare genetic disorder causing debilitating swelling attacks. Their pipeline centers on deucrictibant, an oral bradykinin B2 receptor antagonist designed for both prevention and acute treatment. This is a high-stakes play against established injectable therapies like Takhzyro and Kalbitor.
Traffic & Visibility
With 10,388 monthly visits and a global rank of ~1.8M, Pharvaris operates in a niche B2B biopharma bubble. The traffic is heavily branded (1,410 monthly searches for 'pharvaris'), indicating strong investor and industry interest rather than patient acquisition. The lack of non-branded keyword dominance suggests they are still in the 'story-telling' phase rather than the 'mass-market' phase.
The tech stack reveals a modern, agile approach. Built on Tailwind CSS and Bootstrap with jQuery and Google Analytics, the site is functional but not flashy. It prioritizes data dissemination for investors and the medical community over consumer polish—a smart resource allocation for a company with $10.5M in revenue and 145 employees.
- Late-Stage Focus: Deucrictibant is in pivotal Phase 3 trials (DESOLVE), positioning them for near-term commercialization.
- Oral Administration: A direct challenge to the subcutaneous standard of care, offering convenience and autonomy to patients.
- Leadership Pedigree: CEO Berndt Modig and team bring deep rare disease expertise, critical for navigating FDA pathways and commercialization.
The Verdict: A High-Reward, High-Risk Bet
Pharvaris is a classic biopharma play—everything hinges on clinical data. If deucrictibant succeeds, they become an acquisition target. If it fails, the site becomes a digital ghost. For investors, this is a binary event disguised as a website.
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Pharvaris | Late-Stage Biopharma Company Focused on HAE
Pharvaris is a late-stage biopharma company developing novel, oral bradykinin B2 receptor antagonists to treat and prevent hereditary angioedema attacks.
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About pharvaris.com
Pharvaris is a late-stage biopharma company developing novel, oral bradykinin B2 receptor antagonists to treat and prevent hereditary angioedema attacks.
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Technology Stack
pharvaris.com uses 26 technologies across their website including YouTube Embed, Font Awesome, Adobe Fonts, Laravel, and more.
Video
YouTube Embed
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Font Awesome, Adobe Fonts
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Laravel
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PHP
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Squarespace, Webflow, WordPress
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unpkg, jsDelivr
Traffic & Audience
pharvaris.com receives approximately 10.4K monthly visitors and ranks #1,865,517 globally. The website has a bounce rate of 45% with visitors viewing an average of 2.7 pages per visit. Users spend an average of 1:09 on the site.
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