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iovera: The Non-Opioid Pain Relief Machine
How a 29-person team is disrupting chronic pain with cryoneurolysis and $7.3M in revenue.
While Big Pharma bets billions on addictive opioids, iovera is freezing nerves to stop pain at the source. This isn't a pill—it's a device that uses extreme cold to temporarily shut down pain signals, offering immediate relief for up to 90 days. It’s a bold, drug-free approach to a multi-billion dollar problem.
"iovera isn't treating symptoms; it's literally freezing the pain pathway. That's not innovation—it's a disruption."
The Efficiency Paradox
With only 29 employees generating $7.3M in revenue, iovera operates with exceptional efficiency ($251k revenue per employee). Yet, their web traffic tells a different story: 8,777 monthly visits with a global rank of ~2.7M. This suggests a business model heavily reliant on clinical sales channels and direct physician referrals rather than consumer DTC marketing—a classic med-tech play.
The Search Anomaly
The keyword data reveals a fascinating disconnect. While 'iovera' and 'iovera injection' have modest search volumes, unrelated terms like 'arthrozene' (9,490 monthly volume) and 'freeimg io' dominate the top keywords. This indicates either aggressive SEO experimentation or a misalignment in search intent targeting. The brand has high direct traffic (45%), proving strong recall among patients who know the name, but struggles to capture broad organic discovery.
The tech stack is surprisingly modern for a medical device company. They utilize Tailwind CSS and Bootstrap for rapid frontend development, Swiper for UI interactions, and PWA capabilities for mobile accessibility. However, the reliance on jQuery suggests legacy codebases still in play. The presence of OneTrust indicates compliance with strict healthcare privacy standards (HIPAA/GDPR), a non-negotiable in this space.
- Cryoneurolysis Mechanism: Uses extreme cold to temporarily disrupt nerve function, stopping pain signals before they reach the brain.
- FDA-Cleared & Drug-Free: Positions itself as a safe alternative to opioids, targeting knee, hip, shoulder, and spine pain.
- 90-Day Relief Window: The 'up to 90 days' claim is a critical differentiator, offering a longer duration than most injectable non-opioids.
The Verdict: High Potential, Low Visibility
iovera has the product and the revenue model, but needs to fix its digital discovery strategy to scale beyond clinical channels.
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Meta Tags
iovera | Non-Opioid Pain Relief Treatment
FDA-cleared iovera provides immediate pain relief using cryoneurolysis. Drug-free treatment for knee, hip, shoulder, spine & more. Lasts up to 90 days.
iovera° – Non-Opioid Pain Relief for Knee Pain
iovera° provides targeted, drug-free pain relief using cryoneurolysis for osteoarthritis and post-surgery recovery.
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About iovera.com
FDA-cleared iovera provides immediate pain relief using cryoneurolysis. Drug-free treatment for knee, hip, shoulder, spine & more. Lasts up to 90 days.
Company Overview
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Technology Stack
iovera.com uses 11 technologies across their website including OneTrust, Microsoft Ads, Google Tag Manager, Google Analytics, and more.
Privacy & Consent
OneTrust
Advertising
Microsoft Ads
Analytics & Marketing
Google Tag Manager, Google Analytics
Performance
Lazy Loading
Web Standards
PWA
UI Libraries
DaisyUI
Traffic & Audience
iovera.com receives approximately 8.8K monthly visitors and ranks #2,729,579 globally. The website has a bounce rate of 70% with visitors viewing an average of 1.3 pages per visit. Users spend an average of 0:13 on the site.
The majority of iovera.com's traffic comes from undefined, .
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